RESPOND and REVIVE With CYANOKIT^® Antidote

Introducing CYANOKIT^® Antidote

Designed specifically to be used on the scene or at the hospital for patients with known or suspected acute cyanide (CN) poisoning from smoke inhalation or from any source
Proven generally safe and well-tolerated, even in suspected cases³⁰
Onset of action within minutes⁴⁰
Conveniently packaged and easy-to-administer by paramedics or hospital-based medical personnel
Effectively used in Europe for more than 10 years⁴¹

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Indication
CYANOKIT^® Antidote is indicated for the treatment of known or suspected cyanide poisoning. If clinical suspicion of cyanide poisoning is high, CYANOKIT^® Antidote should be administered without delay.

Important Safety Information
Prior to administration of CYANOKIT^® Antidote, smoke-inhalation victims should be assessed for: exposure to fire or smoke in an enclosed area; presence of soot around the mouth, nose or oropharynx; altered mental status. Use caution in the management of patients with known anaphylactic reactions to hydroxocobalamin or cyanocobalamin. Allergic reactions may include: anaphylaxis, chest tightness, edema, urticaria, pruritus, dyspnea, and rash. Most common adverse reactions (>5%) are transient and include chromaturia (red-colored urine), erythema (skin redness), rash, increased blood pressure, nausea, headache, decreased lymphocyte percent, and injection site reactions. Usage may interfere with some clinical laboratory evaluations. If the decision is made to administer another antidote with CYANOKIT^®, these drugs should not be administered in the same IV line. The safety of simultaneous administration has not been established.

DISCLAIMER
The content of this Web site is not and should not be construed as medical advice. The content contained herein only constitutes commentary and is for educational and information purposes only. Reading this Web site, or any other interaction on this site, does not create a relationship between you and the Web site or its registered owner. As with any medical issue that may confront you in a particular situation, you should always consult a qualified healthcare professional.

This Web site is intended for United States of America (U.S.A.) residents only and is subject to all applicable U.S.A. laws. CYANOKIT^® Antidote is a registered trademark of Merck Santé s.a.s., licensed by Meridian Medical Technologies^®,Inc., a wholly owned subsidiary of King Pharmaceuticals^®, Inc. Copyright © 2009 Meridian Medical Technologies^®, Inc., a wholly owned subsidiary of King Pharmaceuticals^®, Inc. All rights reserved. MMT6577 10/2009

The expert advice of a regional poison control center may be obtained by calling 1-800-222-1222.

RESPOND and REVIVE With CYANOKIT® Antidote

Introducing CYANOKIT® Antidote

RESPOND and REVIVE With CYANOKIT^® Antidote

Introducing CYANOKIT^® Antidote